AIR FLOW AND PARTICLE DEPOSITION IN TRACHEA AND BRANCHES

Objective

Give insight to particle deposition Provide a tool to minimize animal testing Model trachea, carina, and first bifurcations

Results

Effect of particle size on deposition - Flow and particle tracking analyses for a given particle distribution of 1-15 microns Effect of flow rate on deposition Correlation with gamma camera images

Benefits

Simulation of "asthmatic lung" conditions Minimize animal testing Determine if new drugs are practical for inhalation delivery Provide insight to health and safety evaluations