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VIBRO-MIXER SUSPENSION

Objective
  • Provide an understanding of varying flow field inside tank
  • Determine particle concentration distribution
  • Predict shear stresses acting upon insulin crystals
Results
  • Time varying shear rates, fluid velocities & pressures
  • Stagnation points and vorticities in mixer
  • Flow streamlines & particle traces
  • Particle concentration
Benefits
  • Provide detailed understanding of flow distribution
  • Recommend design changes for more homogeneous filling, less waste and higher yield
Process/design parameters
  • Plate vibration frequency & amplitude
  • Plate orifice configuration & shape
  • Plate height
  • Tank fluid level
  • Tank bottom shape
  • Clearance between plate and tank
Performance Evaluations
  • Shear stresses of crystals were found to be high and possible damaging
  • Fluid motion near plate edge
  • Vortex patterns inside tank
  • Areas of high shear stresses acting on crystals:
    - Near plate
    - Inside orifice
    - Inside vortices
 
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